Browsing by Author "Castillo Galán, Sebastián"

Now showing items 1-4 of 4

    • 2-Aminoethyldiphenylborinate modifies the pulmonary circulation in pulmonary hypertensive newborn lambs ... 
      Castillo Galán, Sebastián; Quezada, S.; Moraga, F.; Ebensperger Darrouy, Germán; Herrera, E. A.; Beñaldo, F.; Hernández, I.; Ebensperger, R.; Ramírez, S.; Llanos Mansilla, Jorge; Reyes, R. V. (Amer Physiological Soc., 2016)
      Calcium signaling through store-operated channels (SOC) is involved in hypoxic pulmonary hypertension. We determined whether a treatment with 2-aminoethyldiphenylborinate (2-APB), a compound with SOC blocker activity, ...
    • Cinaciguat (BAY-582667) modifies cardiopulmonary and systemic circulation in chronically hypoxic and pulmonary ... 
      Beñaldo Fuentes, Felipe Augusto; Araya Quijada, Claudio Enrique; Ebensperger Darrouy, Germán; Herrera Videla, Emilio Augusto; Reyes, Roberto V.; Moraga, Fernando A.; Riquelme Herrera, Alexander Nathan; González Candia, Alejandro; Castillo Galán, Sebastián; Valenzuela, Guillermo J.; Serón Ferré, María Josefa; Llanos, Aníbal J. (Frontiers Media, 2022)
      Neonatal pulmonary hypertension (NPHT) is produced by sustained pulmonary vasoconstriction and increased vascular remodeling. Soluble guanylyl cyclase (sGC) participates in signaling pathways that induce vascular vasodilation ...
    • Revisiting the role of TRP, orai, and ASIC channels in the pulmonary arterial response to hypoxia 
      Reyes, Roberto V.; Castillo Galán, Sebastián; Hernández, Ismael; Herrera, Emilio A.; Ebensperger Darrouy, Germán; Llanos Mansilla, Jorge (Frontiers Media S.A., 2018)
      © 2018 Reyes, Castillo-Galán, Hernandez, Herrera, Ebensperger and Llanos. The pulmonary arteries are exquisitely responsive to oxygen changes. They rapidly and proportionally contract as arterial PO2 decrease, and they ...
    • The Action of 2-aminoethyldiphenyl borinate on the pulmonary arterial hypertension and remodeling of ... 
      Castillo Galán, Sebastián; Parrau Vargas, Daniela Beatriz Angela; Hernández Álvarez, Ismael Charles; Quezada, Sebastián; Díaz Navarrete, Marcela; Ebensperger Darrouy, Germán; Herrera Videla, Emilio Augusto; Moraga, Fernando A.; Iturriaga, Rodrigo; Llanos Mansilla, Jorge Aníbal; Reyes Catalán, Víctor Roberto (Frontiers Media, 2022)
      Calcium signaling is key for the contraction, differentiation, and proliferation of pulmonary arterial smooth muscle cells. Furthermore, calcium influx through store-operated channels (SOCs) is particularly important in ...